Custer's Revenge gained notoriety for its plot. Sold in a sealed package labeled "NOT FOR SALE TO MINORS" and selling for $49.95, it acknowledged that children might nonetheless see the game. The game's literature stated "if the kids catch you and should ask, tell them Custer and the maiden are just dancing."
The makers elected to preview the game for women's and Native American groups, an act which some thought was a publicity stunt. The game did prompt criticism from women's rights groups who stated that the game was a simulation of rape; the back of the packaging states "she's not about to take it lying down, by George! Help is on the way. By God! He's coming." Other groups such as Women Against Pornography, Native American spokespersons, and critics of the video game industry in general protested the game. Andrea Dworkin claimed the game "generated many gang rapes of Native American women." Activists tried pressuring legislators to outlaw the game, which Oklahoma City, Oklahoma did. Multiple Industries pursued an $11 million lawsuit against Suffolk County, New York and legislator Philip Nolan "because of a resolution authorizing the county executive to take action to halt sales and distribution" of the game.
This has been credited by Australian PC Magazine as being one of the worst games ever made.